Viral Mutagenesis as a Means for Generating Novel Proteins

Antigen-Specific T Cells A Novel Viral System for Generating

A Novel Toolbox for Generating Realistic Biological Cell Geometries for Electromagnetic Microdosimetry

Researchers in bioelectromagnetics often require realistic tissue, cellular and sub-cellular geometry models for their simulations. However, biological shapes are often extremely irregular, while conventional geometrical modeling tools on the market cannot meet the demand for fast and efficient construction of irregular geometries. We have designed a free, user-friendly tool in MATLAB that comb...

Generating novel allelic variation through Activator insertional mutagenesis in maize.

The maize transposable element Activator (Ac) has been exploited as an insertional mutagen to disrupt, clone, and characterize genes in a number of plant species. To develop an Ac-based mutagenesis platform for maize, a large-scale mutagenesis was conducted targeting the pink scutellum1 locus. We selected 1092 Ac transposition events from a closely linked donor Ac, resulting in the recovery of ...

A new insight into viral proteins as Immunomodulatory therapeutic agents. KSHV vOX2 a homolog of human CD200 as a potent anti-inflammatory protein

The physiologic function of the immune system is defense against infectious microbes and internal tumour cells, Therefore, need to have precise modulatory mechanisms to maintain the body homeostasis. The mammalian cellular CD200 (OX2)/CD200R interaction is one of such modulatory mechanisms in which myeloid and lymphoid cells are regulated. CD200 and CD200R molecules are membrane proteins that t...

cpps-proteins complexes as a novel topical protein delivery system